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Gastrostomy and congenital anomalies: a European population-based study

Garne, E; Tan, J; Loane, M; Baldacci, S; Ballardini, E; Brigden, J; Cavero-Carbonell, C; García-Villodre, L; Gissler, M; Given, J; et al. Garne, E; Tan, J; Loane, M; Baldacci, S; Ballardini, E; Brigden, J; Cavero-Carbonell, C; García-Villodre, L; Gissler, M; Given, J; Heino, A; Jordan, S; Limb, E; Neville, AJ; Rissmann, A; Santoro, M; Scanlon, L; Urhoj, SK; Wellesley, DG; Morris, J (2022) Gastrostomy and congenital anomalies: a European population-based study. BMJ Paediatrics Open, 6 (1). e001526-e001526. ISSN 2399-9772 https://doi.org/10.1136/bmjpo-2022-001526
SGUL Authors: Tan, Joachim Wei Li Morris, Joan Katherine

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Abstract

Objective To report and compare the proportion of children with and without congenital anomalies undergoing gastrostomy for tube feeding in their first 5 years. Methods A European, population-based data-linkage cohort study (EUROlinkCAT). Children up to 5 years of age registered in nine EUROCAT registries (national and regional) in six countries and children without congenital anomalies (reference children) living in the same geographical areas were included. Data on hospitalisation and surgical procedures for all children were obtained by electronic linkage to hospital databases. Results The study included 91 504 EUROCAT children and 1 960 272 reference children. Overall, 1200 (1.3%, 95% CI 1.2% to 1.6%) EUROCAT children and 374 (0.016%, 95% CI 0.009% to 0.026%) reference children had a surgical code for gastrostomy within the first 5 years of life. There were geographical variations across Europe with higher rates in Northern Europe compared with Southern Europe. Around one in four children with Cornelia de Lange syndrome and Wolf-Hirschhorn syndrome had a gastrostomy. Among children with structural anomalies, those with oesophageal atresia had the highest proportion of gastrostomy (15.9%). Conclusions This study including almost 2 million reference children in Europe found that only 0.016% of these children had a surgery code for gastrostomy before age 5 years. The children with congenital anomalies were on average 80 times more likely to need a gastrostomy before age 5 years than children without congenital anomalies. More than two-thirds of gastrostomy procedures performed within the first 5 years of life were in children with congenital anomalies.

Item Type: Article
Additional Information: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
SGUL Research Institute / Research Centre: Academic Structure > Population Health Research Institute (INPH)
Journal or Publication Title: BMJ Paediatrics Open
ISSN: 2399-9772
Language: en
Dates:
DateEvent
June 2022Published
24 June 2022Published Online
9 May 2022Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
733001Horizon 2020UNSPECIFIED
URI: https://openaccess.sgul.ac.uk/id/eprint/114477
Publisher's version: https://doi.org/10.1136/bmjpo-2022-001526

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