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Maternal vaccination: A review of current evidence and recommendations.

Etti, M; Calvert, A; Galiza, E; Lim, S; Khalil, A; Le Doare, K; Heath, PT (2022) Maternal vaccination: A review of current evidence and recommendations. Am J Obstet Gynecol, 226 (4). pp. 459-474. ISSN 1097-6868 https://doi.org/10.1016/j.ajog.2021.10.041
SGUL Authors: Le Doare, Kirsty Heath, Paul Trafford Khalil, Asma Calvert, Anna Louise

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Abstract

Maternal vaccination is an effective means of protecting pregnant women, their fetuses and infants from vaccine-preventable infections. Despite the availability of sufficient safety data to support the use of vaccines during pregnancy, maternal immunization remains an underutilized method of disease prevention, often due to concerns from both healthcare providers and pregnant women about vaccine safety. Such concerns have been reflected in the low uptake of the COVID-19 vaccine among pregnant women seen in many parts of the world, which is due to low vaccine confidence among pregnant women, uncertainty among healthcare professionals and poor access to COVID-19 vaccines. Here we present an update of the current recommendations for the use of vaccines during pregnancy, including the evidence supporting the use of novel vaccine platforms. We also provide an overview of the data supporting the use of COVID-19 vaccines in pregnancy and an update of the status of vaccines that are currently under development for use in pregnant women.

Item Type: Article
Additional Information: © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: 1114 Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Am J Obstet Gynecol
ISSN: 1097-6868
Language: eng
Dates:
DateEvent
31 March 2022Published
11 November 2021Published Online
29 October 2021Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 34774821
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/113871
Publisher's version: https://doi.org/10.1016/j.ajog.2021.10.041

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