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Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution.

Alasfour, S; Alfailakawi, HS; Shamsaldeen, YA (2021) Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution. SAGE Open Med Case Rep, 9. 2050313X211019789. ISSN 2050-313X https://doi.org/10.1177/2050313X211019789
SGUL Authors: Shamsaldeen, Yousif A.Y.M.A

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Abstract

Bartter syndrome is a rare autosomal recessive disorder characterized by hypokalaemia. Hypokalaemia is defined as low serum potassium concentration ˂3.5 mmol/L, which may lead to arrhythmia and death if left untreated. The aim of this case report was to normalize serum potassium concentration without the need for intravenous intervention. A 5-month-old male of 2.7 kg body weight diagnosed with Bartter syndrome was admitted to the general paediatric ward with acute severe hypokalaemia and urinary tract infection. The main challenge was the inability to administer drugs through intravenous route due to compromised body size. Therefore, we shifted the route of administration to the nasogastric tube/oral route. A total of 2 mL of concentrated intravenous potassium chloride (4 mEq potassium) were dissolved in distilled water and administered through nasogastric tube. Serum potassium concentration was rapidly normalized, which culminated in patient discharge. In conclusion, shifting drug administration from intravenous to oral route in a paediatric patient with Bartter syndrome includes numerous advantages such as patient convenience, minimized risk of cannula-induced infection, and reduced nurse workload.

Item Type: Article
Additional Information: © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Keywords: Bartter syndrome, case report, hypokalaemia, kidney, paediatrics, Bartter syndrome, hypokalaemia, paediatrics, kidney, case report
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: SAGE Open Med Case Rep
ISSN: 2050-313X
Language: eng
Dates:
DateEvent
30 May 2021Published
3 May 2021Accepted
Publisher License: Creative Commons: Attribution-Noncommercial 4.0
PubMed ID: 34104447
Web of Science ID: WOS:000693683500001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/113674
Publisher's version: https://doi.org/10.1177/2050313X211019789

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