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Management of Patients with Asymptomatic Carotid Stenosis May Need to Be Individualized: A Multidisciplinary Call for Action.

Paraskevas, KI; Mikhailidis, DP; Baradaran, H; Davies, AH; Eckstein, H-H; Faggioli, G; Fernandes, JFE; Gupta, A; Jezovnik, MK; Kakkos, SK; et al. Paraskevas, KI; Mikhailidis, DP; Baradaran, H; Davies, AH; Eckstein, H-H; Faggioli, G; Fernandes, JFE; Gupta, A; Jezovnik, MK; Kakkos, SK; Katsiki, N; Kooi, ME; Lanza, G; Liapis, CD; Loftus, IM; Millon, A; Nicolaides, AN; Poredos, P; Pini, R; Ricco, J-B; Rundek, T; Saba, L; Spinelli, F; Stilo, F; Sultan, S; Zeebregts, CJ; Chaturvedi, S (2021) Management of Patients with Asymptomatic Carotid Stenosis May Need to Be Individualized: A Multidisciplinary Call for Action. J Stroke, 23 (2). pp. 202-212. ISSN 2287-6391 https://doi.org/10.5853/jos.2020.04273
SGUL Authors: Loftus, Ian

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Abstract

The optimal management of patients with asymptomatic carotid stenosis (ACS) is the subject of extensive debate. According to the 2017 European Society for Vascular Surgery guidelines, carotid endarterectomy should (Class IIa; Level of Evidence: B) or carotid artery stenting may be considered (Class IIb; Level of Evidence: B) in the presence of one or more clinical/imaging characteristics that may be associated with an increased risk of late ipsilateral stroke (e.g., silent embolic infarcts on brain computed tomography/magnetic resonance imaging, progression in the severity of ACS, a history of contralateral transient ischemic attack/stroke, microemboli detection on transcranial Doppler, etc.), provided documented perioperative stroke/death rates are <3% and the patient's life expectancy is >5 years. Besides these clinical/imaging characteristics, there are additional individual, ethnic/racial or social factors that should probably be evaluated in the decision process regarding the optimal management of these patients, such as individual patient needs/patient choice, patient compliance with best medical treatment, patient sex, culture, race/ethnicity, age and comorbidities, as well as improvements in imaging/operative techniques/outcomes. The present multispecialty position paper will present the rationale why the management of patients with ACS may need to be individualized.

Item Type: Article
Additional Information: Copyright © 2021 Korean Stroke SocietyThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Carotid stenosis, Endarterectomy, carotid, Ischemic attack, transient, Life expectancy, Patient preference, Stroke, Endarterectomy, carotid, Carotid stenosis, Stroke, Ischemic attack, transient, Patient preference, Life expectancy
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: J Stroke
ISSN: 2287-6391
Language: eng
Dates:
DateEvent
31 May 2021Published
12 April 2021Accepted
Publisher License: Creative Commons: Attribution-Noncommercial 4.0
PubMed ID: 34102755
Web of Science ID: WOS:000656888500005
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/113363
Publisher's version: https://doi.org/10.5853/jos.2020.04273

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