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Percutaneous management of lead-related cardiac perforation with limited use of computed tomography and cardiac surgery.

Elbatran, AI; Akhtar, Z; Bajpai, A; Leung, L; Li, A; Pearse, S; Zuberi, Z; Kaba, R; Saba, MM; Norman, M; et al. Elbatran, AI; Akhtar, Z; Bajpai, A; Leung, L; Li, A; Pearse, S; Zuberi, Z; Kaba, R; Saba, MM; Norman, M; Grimster, A; Gallagher, MM; Sohal, M (2021) Percutaneous management of lead-related cardiac perforation with limited use of computed tomography and cardiac surgery. Pacing Clin Electrophysiol, 44 (4). pp. 614-624. ISSN 1540-8159 https://doi.org/10.1111/pace.14204
SGUL Authors: Leung, Lisa

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Abstract

BACKGROUND: Cardiac implantable electronic device (CIED)-related perforation is uncommon but potentially lethal. Management typically includes the use of computed tomography (CT) scanning and often involves cardiac surgery. METHODS: Patients presenting to a single referral centre with CIED-related cardiac perforation between 2013 and 2019 were identified. Demographics, diagnostic modalities, the method of lead revision and 30-day complications were examined. RESULTS: Forty-six cases were identified; median time from implantation to diagnosis was 14 days (IQR = 4-50). Most were females (29/46, 63%), 9/46 (20%) had cancer,18 patients (39%) used oral anticoagulants and no patients had prior cardiac surgery. Active fixation was involved in 98% of cases; 9% involved an ICD lead. Thirty-seven leads perforated the right ventricle (apex: 24) and 9 punctured the right atrium (lateral wall: 5). Abnormal electrical parameters were noted in 95% of interrogated cases. Perforation was visualized in 41% and 6% of cases with CXR and transthoracic echocardiography, respectively. CXR revealed a perforation, gross lead displacement or left-sided pleural effusion in 74% of cases. Pericardial effusion occurred in 26 patients (57%) of whom 11 (24%) developed tamponade, successfully drained percutaneously. Pre-extraction CT scan was performed in 19 patients but was essential in 4 cases. Transvenous lead revision (TLR) was successfully performed in all cases with original leads repositioned in 6 patients, without recourse to surgery. Thirty-day mortality and complications were low (0% & 26%, respectively). CONCLUSION: CT scanning provides incremental diagnostic value in a minority of CIED-related perforations. TLR is a safe and effective strategy. This article is protected by copyright. All rights reserved.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Elbatran, AI, Akhtar, Z, Bajpai, A, et al. Percutaneous management of lead‐related cardiac perforation with limited use of computed tomography and cardiac surgery. Pacing Clin Electrophysiol. 2021; 44: 614– 624, which has been published in final form at https://doi.org/10.1111/pace.14204. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Keywords: Cardiac perforation, cardiac implantable electronic devices, defibrillator, pacemaker, transvenous lead revision, Cardiovascular System & Hematology, 0903 Biomedical Engineering, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Pacing Clin Electrophysiol
ISSN: 1540-8159
Language: eng
Dates:
DateEvent
9 April 2021Published
8 March 2021Published Online
21 February 2021Accepted
Publisher License: Publisher's own licence
PubMed ID: 33624296
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/113020
Publisher's version: https://doi.org/10.1111/pace.14204

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