SORA

Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

Social gradient of birthweight in England assessed using the INTERGROWTH-21st gestational age-specific standard.

Hirst, JE; Knight, HE; Ohuma, EO; Dwyer, T; Hennig, BD; Papageorghiou, AT; Cheikh Ismail, L; Villar, J; Kennedy, SH (2019) Social gradient of birthweight in England assessed using the INTERGROWTH-21st gestational age-specific standard. Arch Dis Child Fetal Neonatal Ed, 104 (5). F486-F492. ISSN 1468-2052 https://doi.org/10.1136/archdischild-2018-315295
SGUL Authors: Papageorghiou, Aris

[img]
Preview
PDF Accepted Version
Available under License ["licenses_description_publisher" not defined].

Download (115kB) | Preview

Abstract

OBJECTIVE: To determine the socioeconomic gradient of birthweights in England with reference to the prescriptive INTERGROWTH-21st Birthweight Standard. DESIGN: National cross-sectional study using data from Hospital Episode Statistics. SETTING: National Health Service in England. PARTICIPANTS: All singleton babies, live born between 34 weeks' gestation and 42 weeks' gestation, between 1 April 2011 and 31 March 2012. MAIN OUTCOME MEASURES: Birthweight distribution of babies with a birthweight of <10th centile or >90th centile, that is, small for gestational age (SGA) or large for gestational age (LGA) using Index of Multiple Deprivation quintiles as a proxy for socioeconomic status. RESULTS: Of 508 230 babies born alive between 1 April 2011 and 31 March 2012, 38 838 (7.6%) were SGA and 81 026 (15.9%) were LGA. Median birthweight was 3405 g, median z-score was 0.25 (SD 1.06). Birthweight z-score demonstrated a social gradient, from 0.26 (SD 1.1) in the most deprived areas to 0.53 (1.0) in the least deprived. Women in the most deprived areas were twice as likely to have SGA babies using the INTERGROWTH-21st chart (OR 1.94; 95% CI 1.87 to 2.01) compared with those in the least deprived areas. If all women had the same rate of SGA equivalent to those living in the least deprived areas, approximately 12 410 (30%) fewer babies would be born SGA in England each year. CONCLUSIONS: This study gives a measure of the social gradient in singleton SGA and LGA babies across England using an international standard of newborn size at birth.

Item Type: Article
Additional Information: This article has been accepted for publication in Archives of Disease in Childhood: Fetal & Neonatal, 2019 following peer review, and the Version of Record can be accessed online at http://dx.doi.org/10.1136/archdischild-2018-315295. © Author(s) (or their employer(s)) 2019.
Keywords: England, birthweight, large for gestational age, small for gestational age, socioeconomic, Biometry, Birth Weight, Cross-Sectional Studies, England, Female, Gestational Age, Humans, Infant, Newborn, Infant, Small for Gestational Age, Male, Pregnancy, Pregnancy Outcome, Reference Values, Social Determinants of Health, Socioeconomic Factors, Humans, Birth Weight, Pregnancy Outcome, Cross-Sectional Studies, Biometry, Gestational Age, Pregnancy, Reference Values, Socioeconomic Factors, Infant, Newborn, Infant, Small for Gestational Age, England, Female, Male, Social Determinants of Health, England, birthweight, large for gestational age, small for gestational age, socioeconomic, Biometry, Birth Weight, Cross-Sectional Studies, England, Female, Gestational Age, Humans, Infant, Newborn, Infant, Small for Gestational Age, Male, Pregnancy, Pregnancy Outcome, Reference Values, Social Determinants of Health, Socioeconomic Factors, Pediatrics, 1114 Paediatrics and Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Arch Dis Child Fetal Neonatal Ed
ISSN: 1468-2052
Language: eng
Dates:
DateEvent
19 August 2019Published
21 November 2018Published Online
9 October 2018Accepted
Publisher License: Publisher's own licence
PubMed ID: 30464006
Web of Science ID: WOS:000501744900007
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112951
Publisher's version: https://doi.org/10.1136/archdischild-2018-315295

Actions (login required)

Edit Item Edit Item