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Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio‐Oncology Council of the European Society of Cardiology (ESC)

Čelutkienė, J; Pudil, R; López-Fernández, T; Grapsa, J; Nihoyannopoulos, P; Bergler-Klein, J; Cohen-Solal, A; Farmakis, D; Tocchetti, CG; von Haehling, S; et al. Čelutkienė, J; Pudil, R; López-Fernández, T; Grapsa, J; Nihoyannopoulos, P; Bergler-Klein, J; Cohen-Solal, A; Farmakis, D; Tocchetti, CG; von Haehling, S; Barberis, V; Flachskampf, FA; Čeponienė, I; Haegler-Laube, E; Suter, T; Lapinskas, T; Prasad, S; de Boer, RA; Wechalekar, K; Anker, MS; Iakobishvili, Z; Buccarelli-Ducci, C; Schulz-Menger, J; Cosyns, B; Gaemperli, O; Belenkov, Y; Hulot, J-S; Galderisi, M; Lancellotti, P; Bax, J; Marwick, TH; Chioncel, O; Jaarsma, T; Mullens, W; Piepoli, M; Thum, T; Heymans, S; Mueller, C; Moura, B; Ruschitzka, F; Zamorano, JL; Rosano, G; Coats, AJS; Asteggiano, R; Seferovic, P; Edvardsen, T; Lyon, AR (2020) Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio‐Oncology Council of the European Society of Cardiology (ESC). Eur J Heart Fail, 22 (9). pp. 1504-1524. ISSN 1879-0844 https://doi.org/10.1002/ejhf.1957
SGUL Authors: Rosano, Giuseppe Massimo Claudio

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Abstract

Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position statement examines the role of echocardiography, cardiac magnetic resonance, nuclear cardiac imaging and computed tomography in the management of cancer patients. The Imaging and Cardio‐Oncology Study Groups of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) in collaboration with the European Association of Cardiovascular Imaging (EACVI) and the Cardio‐Oncology Council of the ESC have evaluated the current evidence for the value of modern CV imaging in the cardio‐oncology field. The most relevant echocardiographic parameters, including global longitudinal strain and three‐dimensional ejection fraction, are proposed. The protocol for baseline pre‐treatment evaluation and specific surveillance algorithms or pathways for anthracycline chemotherapy, HER2‐targeted therapies such as trastuzumab, vascular endothelial growth factor tyrosine kinase inhibitors, BCr‐Abl tyrosine kinase inhibitors, proteasome inhibitors and immune checkpoint inhibitors are presented. The indications for CV imaging after completion of oncology treatment are considered. The typical consequences of radiation therapy and the possibility of their identification in the long term are also summarized. Special populations are discussed including female survivors planning pregnancy, patients with carcinoid disease, patients with cardiac tumours and patients with right heart failure. Future directions and ongoing CV imaging research in cardio‐oncology are discussed.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Čelutkienė, J., Pudil, R., López‐Fernández, T., Grapsa, J., Nihoyannopoulos, P., Bergler‐Klein, J., Cohen‐Solal, A., Farmakis, D., Tocchetti, C.G., von Haehling, S., Barberis, V., Flachskampf, F.A., Čeponienė, I., Haegler‐Laube, E., Suter, T., Lapinskas, T., Prasad, S., de Boer, R.A., Wechalekar, K., Anker, M.S., Iakobishvili, Z., Bucciarelli‐Ducci, C., Schulz‐Menger, J., Cosyns, B., Gaemperli, O., Belenkov, Y., Hulot, J.‐S., Galderisi, M., Lancellotti, P., Bax, J., Marwick, T.H., Chioncel, O., Jaarsma, T., Mullens, W., Piepoli, M., Thum, T., Heymans, S., Mueller, C., Moura, B., Ruschitzka, F., Zamorano, J.L., Rosano, G., Coats, A.J., Asteggiano, R., Seferovic, P., Edvardsen, T. and Lyon, A.R. (2020), Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio‐Oncology Council of the European Society of Cardiology (ESC). Eur J Heart Fail, 22: 1504-1524., which has been published in final form at https://doi.org/10.1002/ejhf.1957. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Correction available at https://doi.org/10.1002/ejhf.2153
Keywords: cardiac magnetic resonance, cardio-oncology, cardiotoxicity, computed tomography, echocardiography, global longitudinal strain, heart failure, imaging, nuclear imaging, Cardiovascular System & Hematology, 1102 Cardiorespiratory Medicine and Haematology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Eur J Heart Fail
ISSN: 1879-0844
Language: eng
Dates:
DateEvent
29 October 2020Published
21 August 2020Published Online
1 July 2020Accepted
Publisher License: Publisher's own licence
Projects:
Project IDFunderFunder ID
2014-40Netherlands Heart FoundationUNSPECIFIED
2017-21Netherlands Heart FoundationUNSPECIFIED
2017-11Netherlands Heart FoundationUNSPECIFIED
ERC CoG 818715European Research Councilhttp://dx.doi.org/10.13039/501100000781
PubMed ID: 32621569
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112154
Publisher's version: https://doi.org/10.1002/ejhf.1957

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