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Left ventricular remodeling in elite and sub-elite road cyclists.

Brown, B; Millar, L; Somauroo, J; George, K; Sharma, S; La Gerche, A; Forsythe, L; Oxborough, D (2020) Left ventricular remodeling in elite and sub-elite road cyclists. Scand J Med Sci Sports, 30 (7). pp. 1132-1139. ISSN 1600-0838 https://doi.org/10.1111/sms.13656
SGUL Authors: Sharma, Sanjay

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Abstract

Marked adaptation of left ventricular (LV) structure in endurance athletes is well established. However, previous investigations of functional and mechanical adaptation have been contradictory. A lack of clarity in subjects' athletic performance level may have contributed to these disparate findings. This study aimed to describe structural, functional, and mechanical characteristics of the cyclists' LV, based on clearly defined performance levels. Male elite cyclists (EC) (n = 69), sub-elite cyclists (SEC) (n = 30), and non-athletes (NA) (n = 46) were comparatively studied using conventional and speckle tracking 2D echocardiography. Dilated eccentric hypertrophy was common in EC (34.7%), but not SEC (3.3%). Chamber concentricity was higher in EC compared to SEC (7.11 ± 1.08 vs 5.85 ± 0.98 g/(mL)2/3 , P < .001). Ejection fraction (EF) was lower in EC compared to NA (57 ± 5% vs 59 ± 4%, P < .05), and reduced EF was observed in a greater proportion of EC (11.6%) compared to SEC (6.7%). Global circumferential strain (GCε) was greater in EC (-18.4 ± 2.4%) and SEC (-19.8 ± 2.7%) compared to NA (-17.2 ± 2.6%) (P < .05 and P < .001). Early diastolic filling was lower in EC compared with SEC (0.72 ± 0.14 vs 0.88 ± 0.12 cm/s, P < .001), as were septal E' (12 ± 2 vs 15 ± 2 cm/s, P < .001) and lateral E' (18 ± 4 vs 20 ± 4 cm/s, P < .05). The magnitude of LV structural adaptation was far greater in EC compared with SEC. Increased GCε may represent a compensatory mechanism to maintain stroke volume in the presence of increased chamber volume. Decreased E and E' velocities may be indicative of a considerable functional reserve in EC.

Item Type: Article
Additional Information: © 2020 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: athlete's heart, cycling, echocardiography, left ventricular geometry, physiological adaptation to exercise, athlete's heart, cycling, echocardiography, left ventricular geometry, physiological adaptation to exercise, 1106 Human Movement and Sports Sciences, Sport Sciences
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Scand J Med Sci Sports
ISSN: 1600-0838
Language: eng
Dates:
DateEvent
16 June 2020Published
4 April 2020Published Online
11 March 2020Accepted
Publisher License: Creative Commons: Attribution-Noncommercial 4.0
PubMed ID: 32187398
Web of Science ID: WOS:000523237000001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/111799
Publisher's version: https://doi.org/10.1111/sms.13656

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