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Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study.

Pearson-Stuttard, J; Critchley, J; Capewell, S; O'Flaherty, M (2015) Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study. PLoS One, 10 (8). e0132524. ISSN 1932-6203
SGUL Authors: Critchley, Julia

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BACKGROUND: Coronary Heart Disease (CHD) remains a leading cause of UK mortality, generating a large and unequal burden of disease. Dietary trans fatty acids (TFA) represent a powerful CHD risk factor, yet to be addressed in the UK (approximately 1% daily energy) as successfully as in other nations. Potential outcomes of such measures, including effects upon health inequalities, have not been well quantified. We modelled the potential effects of specific reductions in TFA intake on CHD mortality, CHD related admissions, and effects upon socioeconomic inequalities. METHODS & RESULTS: We extended the previously validated IMPACTsec model, to estimate the potential effects of reductions (0.5% & 1% reductions in daily energy) in TFA intake in England and Wales, stratified by age, sex and socioeconomic circumstances. We estimated reductions in expected CHD deaths in 2030 attributable to these two specific reductions. Output measures were deaths prevented or postponed, life years gained and hospital admissions. A 1% reduction in TFA intake energy intake would generate approximately 3,900 (95% confidence interval (CI) 3,300-4,500) fewer deaths, 10,000 (8,800-10,300) (7% total) fewer hospital admissions and 37,000 (30,100-44,700) life years gained. This would also reduce health inequalities, preventing five times as many deaths and gaining six times as many life years in the most deprived quintile compared with the most affluent. A more modest reduction (0.5%) would still yield substantial health gains. CONCLUSIONS: Reducing intake of industrial TFA could substantially decrease CHD mortality and hospital admissions, and gain tens of thousands of life years. Crucially, this policy could also reduce health inequalities. UK strategies should therefore aim to minimise industrial TFA intake.

Item Type: Article
Additional Information: Copyright: © 2015 Pearson-Stuttard et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Keywords: Adult, Age Factors, Aged, Coronary Artery Disease, Dietary Fats, Female, Humans, Male, Middle Aged, Models, Theoretical, Risk Factors, Sex Factors, Socioeconomic Factors, Trans Fatty Acids, Humans, Dietary Fats, Trans Fatty Acids, Risk Factors, Age Factors, Sex Factors, Models, Theoretical, Socioeconomic Factors, Adult, Aged, Middle Aged, Female, Male, Coronary Artery Disease, MD Multidisciplinary, General Science & Technology
SGUL Research Institute / Research Centre: Academic Structure > Population Health Research Institute (INPH)
Journal or Publication Title: PLoS One
ISSN: 1932-6203
Language: eng
6 August 2015Published
15 June 2015Accepted
Publisher License: Creative Commons: Attribution 4.0
Project IDFunderFunder ID
UNSPECIFIEDMedical Research Council
223705Seventh Framework Programme
PubMed ID: 26247848
Web of Science ID: WOS:000359062300007
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