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Psychiatric aspects of posttraumatic epilepsy: A still unexplored area.

Mula, M (2019) Psychiatric aspects of posttraumatic epilepsy: A still unexplored area. Epilepsy Behav, 101 (A). p. 106598. ISSN 1525-5069 https://doi.org/10.1016/j.yebeh.2019.106598
SGUL Authors: Mula, Marco

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Abstract

Traumatic brain injury (TBI) represents one of the most common causes of death and disability in young people, and posttraumatic epilepsy (PTE) accounts for 10% to 20% of all symptomatic epilepsies. However, PTE is still a relatively underappreciated condition. This paper aimed at reviewing current knowledge about psychiatric comorbidities of PTE, looking in particular at the nature of the relationship between TBI, psychiatric problems, and epilepsy, at the phenomenology of psychiatric disorders in PTE, and how to manage them. Data on psychiatric comorbidities of PTE are almost nonexistent, and this is a paradox considering that TBI itself is burdened by a number of cognitive and psychiatric sequelae, which can profoundly affect the everyday life of these patients. Preliminary data seem to suggest that the bidirectional relationship between epilepsy and psychiatric disorders is maintained in TBI and people with a psychiatric condition at the time of the TBI, or as a consequence of it, are at increased risk of developing PTE and vice versa. However, a number of questions are still unanswered concerning the genetic and environmental contributors, the phenomenology of psychiatric disorders in PTE, and how to prevent and address them properly. Further research in this area is urgently needed in order to provide the best possible care to people with PTE. Special Issue: Epilepsy & Behavior's 20th Anniversary.

Item Type: Article
Additional Information: © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Agitation, Antidepressants, Antiepileptic drugs, Depression, Posttraumatic epilepsy, Traumatic brain injury, 1103 Clinical Sciences, Neurology & Neurosurgery
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Epilepsy Behav
ISSN: 1525-5069
Language: eng
Dates:
DateEvent
December 2019Published
31 October 2019Published Online
2 October 2019Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 31677996
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/111410
Publisher's version: https://doi.org/10.1016/j.yebeh.2019.106598

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