SORA

Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

Compensating control participants when the intervention is of significant value: experience in Guatemala, India, Peru and Rwanda

Quinn, AK; Williams, K; Thompson, LM; Rosa, G; Diaz-Artiga, A; Thangavel, G; Balakrishnan, K; Miranda, JJ; Rosenthal, JP; Clasen, TF; et al. Quinn, AK; Williams, K; Thompson, LM; Rosa, G; Diaz-Artiga, A; Thangavel, G; Balakrishnan, K; Miranda, JJ; Rosenthal, JP; Clasen, TF; Harvey, SA; Aravindalochanan, V; Barr, DB; Burrowes, V; Campbell, D; Campbell, JM; Canuz, E; Castanaza, A; Chang, H; Checkley, W; Chen, Y; Chiang, M; Clark, ML; Craik, R; Crocker, M; Davila-Roman, V; de la Fuentes, L; De Leon, O; Dusabimana, E; Elon, L; Gabriel Espinoza, J; Pineda Fuentes, IS; Garg, S; Goodman, D; Gupton, S; Hardison, M; Hartinger, S; Herrera, P; Hossen, S; Jaacks, L; Jabbarzadeh, S; Johnson, MA; Jones, A; Kearns, K; Kirby, M; Kremer, J; Laws, M; Liao, J; Lovvorn, A; Majorin, F; McCollum, E; McCracken, J; Meyers, R; Mollinedo, E; Moulton, L; Mukhopadhyay, K; Naeher, L; Nambajimana, A; Ndagijimana, F; Nizam, A; Ntivuguruzwa, JDD; Papageorghiou, A; Peel, J; Piedrahita, R; Pillarisetti, A; Puttaswamy, N; Puzzolo, E; Rajkumar, S; Ramakrishnan, U; Reardon, D; Ryan, PB; Sakas, Z; Sambandam, S; Sarnat, J; Simkovich, S; Sinharoy, S; Smith, KR; Steenland, K; Swearing, D; Toenjes, A; Underhill, L; Uwizeyimana, JD; Valdes, V; Verma, A; Waller, L; Warnock, M; Young, B; Investigators, HAPIN (2019) Compensating control participants when the intervention is of significant value: experience in Guatemala, India, Peru and Rwanda. BMJ GLOBAL HEALTH, 4 (4). e001567. ISSN 2059-7908 https://doi.org/10.1136/bmjgh-2019-001567
SGUL Authors: Papageorghiou, Aris

[img]
Preview
PDF Published Version
Available under License Creative Commons Attribution.

Download (291kB) | Preview

Abstract

The Household Air Pollution Intervention Network (HAPIN) trial is a randomised controlled trial in Guatemala, India, Peru and Rwanda to assess the health impact of a clean cooking intervention in households using solid biomass for cooking. The HAPIN intervention—a liquefied petroleum gas (LPG) stove and 18-month supply of LPG—has significant value in these communities, irrespective of potential health benefits. For control households, it was necessary to develop a compensation strategy that would be comparable across four settings and would address concerns about differential loss to follow-up, fairness and potential effects on household economics. Each site developed slightly different, contextually appropriate compensation packages by combining a set of uniform principles with local community input. In Guatemala, control compensation consists of coupons equivalent to the LPG stove’s value that can be redeemed for the participant’s choice of household items, which could include an LPG stove. In Peru, control households receive several small items during the trial, plus the intervention stove and 1 month of fuel at the trial’s conclusion. Rwandan participants are given small items during the trial and a choice of a solar kit, LPG stove and four fuel refills, or cash equivalent at the end. India is the only setting in which control participants receive the intervention (LPG stove and 18 months of fuel) at the trial’s end while also being compensated for their time during the trial, in accordance with local ethics committee requirements. The approaches presented here could inform compensation strategy development in future multi-country trials.

Item Type: Article
Additional Information: © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
Keywords: randomised controlled trial, compensation, ethics, multi-country trial
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: BMJ GLOBAL HEALTH
ISSN: 2059-7908
Dates:
DateEvent
21 August 2019Published
5 July 2019Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
1UM1HL134590National Institutes of Healthhttp://dx.doi.org/10.13039/100000002
OPP1131279Bill and Melinda Gates Foundationhttp://dx.doi.org/10.13039/100000865
Web of Science ID: WOS:000489068600030
URI: https://openaccess.sgul.ac.uk/id/eprint/111354
Publisher's version: https://doi.org/10.1136/bmjgh-2019-001567

Actions (login required)

Edit Item Edit Item