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Do we need a core outcome set for childbirth perineal trauma research? A systematic review of outcome reporting in randomised trials evaluating the management of childbirth trauma.

Pergialiotis, V; Durnea, C; Elfituri, A; Duffy, J; Doumouchtsis, SK; International Collaboration for Harmonising Outcomes, Research, (2018) Do we need a core outcome set for childbirth perineal trauma research? A systematic review of outcome reporting in randomised trials evaluating the management of childbirth trauma. BJOG, 125 (12). pp. 1522-1531. ISSN 1471-0528 https://doi.org/10.1111/1471-0528.15408
SGUL Authors: Doumouchtsis, Stergios

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Abstract

BACKGROUND: Selecting appropriate outcomes to reflect both beneficial and harmful effects is a critical step in designing childbirth trauma trials. OBJECTIVE: To evaluate the outcomes and outcome measures reported in randomised controlled trials evaluating interventions for childbirth trauma. SEARCH STRATEGY: Randomised trials were identified by searching bibliographical databases including the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and EMBASE. SELECTION CRITERIA: Randomised trials evaluating the efficacy and safety of different techniques in the management of perineal lacerations. DATA COLLECTION AND ANALYSIS: Two researchers independently assessed studies for inclusion, evaluated methodological quality, and extracted the relevant data. Spearman's ρ correlation and multivariate linear regression analysis using the backward stepwise model were used for analysis. MAIN RESULTS: Forty-eight randomised trials, reporting data from 20 308 women, were included. Seventeen different interventions were evaluated. Included trials reported 77 different outcomes and 50 different outcome measures. Commonly reported outcomes included pain (34 trials; 70%), wound healing (20 trials; 42%), and anorectal dysfunction (16 trials, 33%). In the multivariate analysis, no relationship was demonstrated between the quality of outcome reporting and year of publication (P = 0.31), journal impact factor (P = 0.49), and methodological quality (P = 0.13). CONCLUSION: Outcome reporting in childbirth trauma research is heterogeneous. Developing, disseminating, and implementing a core outcome set in future childbirth trauma research could help address these issues. TWEETABLE ABSTRACT: Developing @coreoutcomes for childbirth trauma research could help to reduce #research waste.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Pergialiotis, V, Durnea, C, Elfituri, A, Duffy, JMN, Doumouchtsis, SK, on behalf of the International Collaboration for Harmonising Outcomes, Research, and Standards in Urogynaecology and Women's Health (CHORUS). Do we need a core outcome set for childbirth perineal trauma research? A systematic review of outcome reporting in randomised trials evaluating the management of childbirth trauma. BJOG 2018; 125: 1522– 1531, which has been published in final form at https://doi.org/10.1111/1471-0528.15408. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Keywords: Childbirth trauma, core outcome sets, lacerations, outcome variation, perineal trauma, Delivery, Obstetric, Female, Humans, Obstetric Labor Complications, Outcome Assessment (Health Care), Perineum, Pregnancy, Randomized Controlled Trials as Topic, Research Design, International Collaboration for Harmonising Outcomes, Research, and Standards in Urogynaecology and Women's Health (CHORUS), Perineum, Humans, Delivery, Obstetric, Pregnancy, Research Design, Outcome Assessment (Health Care), Female, Obstetric Labor Complications, Randomized Controlled Trials as Topic, Childbirth trauma, core outcome sets, lacerations, outcome variation, perineal trauma, Childbirth trauma, core outcome sets, lacerations, outcome variation, perineal trauma, Delivery, Obstetric, Female, Humans, Obstetric Labor Complications, Outcome Assessment (Health Care), Perineum, Pregnancy, Randomized Controlled Trials as Topic, Research Design, 11 Medical And Health Sciences, Obstetrics & Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: BJOG
ISSN: 1471-0528
Language: eng
Dates:
DateEvent
10 October 2018Published
25 September 2018Published Online
1 May 2018Accepted
Publisher License: Publisher's own licence
PubMed ID: 30009461
Web of Science ID: WOS:000446823500007
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/110882
Publisher's version: https://doi.org/10.1111/1471-0528.15408

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