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Latent tuberculosis infection and non-infectious co-morbidities: Diabetes mellitus type 2, chronic kidney disease and rheumatoid arthritis.

Ugarte-Gil, C; Carrillo-Larco, RM; Kirwan, DE (2019) Latent tuberculosis infection and non-infectious co-morbidities: Diabetes mellitus type 2, chronic kidney disease and rheumatoid arthritis. Int J Infect Dis, 80S. S29-S31. ISSN 1878-3511 https://doi.org/10.1016/j.ijid.2019.02.018
SGUL Authors: Kirwan, Daniela Elisa

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Abstract

The prevalence of non-communicable diseases is increasing worldwide, which coincides with the persistence of infectious diseases including tuberculosis. These can synergistically affect individual and population health. Three non-communicable diseases that are relevant because of their associated morbidity, mortality and disability are type 2 diabetes mellitus, chronic kidney disease and rheumatoid arthritis. There is some evidence that patients with these conditions are at increased risk of acquiring latent tuberculosis infection (LTBI) and of this progressing to active disease. Unfortunately, evidence on accurate testing and effective prophylactic treatment in these populations is lacking. This review discusses current evidence and recommendations for management of LTBI in these patients.

Item Type: Article
Additional Information: © 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Chronic kidney disease and Rheumatoid arthritis, Diabetes mellitus type 2, Tuberculosis, Tuberculosis, Diabetes mellitus type 2, Chronic kidney disease and Rheumatoid arthritis, 0605 Microbiology, 1108 Medical Microbiology, Microbiology
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Int J Infect Dis
ISSN: 1878-3511
Language: eng
Dates:
DateEvent
March 2019Published
22 February 2019Published Online
18 February 2019Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 30802622
Web of Science ID: WOS:000460660800008
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/110780
Publisher's version: https://doi.org/10.1016/j.ijid.2019.02.018

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