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Induced sputum is safe and well-tolerated for TB diagnosis in a resource-poor primary healthcare setting.

Ugarte-Gil, C; Elkington, PT; Gotuzzo, E; Friedland, JS; Moore, DAJ (2015) Induced sputum is safe and well-tolerated for TB diagnosis in a resource-poor primary healthcare setting. Am J Trop Med Hyg, 92 (3). pp. 633-635. ISSN 1476-1645
SGUL Authors: Friedland, Jonathan Samuel

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Improved tuberculosis (TB) diagnostics are required. Induced sputum sampling is superior to spontaneous sputum analysis for diagnosis of pulmonary TB. Therefore, we examined the applicability of induced sputum in primary health centers of the Peruvian TB program and studied the safety and tolerability of this procedure. We show that induced sputum is safe, inexpensive, and well-tolerated in a resource-limited environment. Widespread use of induced sputum at primary health centers can be implemented and may improve TB diagnosis.

Item Type: Article
Additional Information: This is an open-access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: Adult, Female, Humans, Male, Peru, Primary Health Care, Saline Solution, Hypertonic, Sputum, Tuberculosis, Sputum, Humans, Tuberculosis, Saline Solution, Hypertonic, Adult, Primary Health Care, Peru, Female, Male, Science & Technology, Life Sciences & Biomedicine, Public, Environmental & Occupational Health, Tropical Medicine, PULMONARY TUBERCULOSIS, INDUCTION, MICROSCOPY, COMMUNITY, AEROSOL, LAVAGE, 11 Medical And Health Sciences, Tropical Medicine
Journal or Publication Title: Am J Trop Med Hyg
ISSN: 1476-1645
Language: eng
March 2015Published
22 December 2014Published Online
9 November 2014Accepted
Publisher License: Creative Commons: Attribution 4.0
Project IDFunderFunder ID
085777/Z/08/ZWellcome Trust
PubMed ID: 25535311
Web of Science ID: WOS:000350529400036
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