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Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales.

Makwana, A; Ladhani, SN; Kapatai, G; Campion, E; Fry, NK; Sheppard, C (2018) Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales. Emerg Infect Dis, 24 (10). pp. 1919-1922. ISSN 1080-6059 https://doi.org/10.3201/eid2410.180114
SGUL Authors: Ladhani, Shamez Nizarali

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Abstract

We observed a sudden and rapid increase in rare invasive pneumococcal disease serotype 7C, from an annual average of 3 cases during 2000-01 through 2015-16 to 29 cases in 2016-17. The increase was caused almost entirely by clonal expansion of sequence type 177, previously associated with vaccine serotype 19F.

Item Type: Article
Additional Information: Emerging Infectious Diseases is an open access journal in the public domain. All content is freely available without charge to the user or his/her institution. In accordance with the Budapest Open Access Initiative (http://budapestopenaccessinitiative.org/) definition of Open Access, users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. Because the journal is in the public domain, its usage policy also conforms to conditions set for by Creative Commons (https://creativecommons.org/licenses/by/4.0/). Emerging Infectious Diseases does request a proper citation be included for its content and that any user indicate clearly if changes have been made.
Keywords: England, ST177, Streptococcus pneumoniae, United Kingdom, Wales, bacteria, capsular switching, invasive pneumococcal disease, pneumococcal conjugate vaccines, replacement disease, sequence type, serotype, serotype 7C, 1108 Medical Microbiology, 1117 Public Health And Health Services, 1103 Clinical Sciences, Microbiology
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Emerg Infect Dis
ISSN: 1080-6059
Language: eng
Dates:
DateEvent
October 2018Published
28 August 2018Published Online
Publisher License: Publisher's own licence
PubMed ID: 30226184
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/110375
Publisher's version: https://doi.org/10.3201/eid2410.180114

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