Advancing, promoting and sharing knowledge of health through excellence in teaching, clinical practice and research into the prevention and treatment of illness

Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador.

Cooper, PJ; Chico, ME; Platts-Mills, TA; Rodrigues, LC; Strachan, DP; Barreto, ML (2015) Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador. International Journal of Epidemiology, 44 (5). pp. 1517-1527. ISSN 1464-3685
SGUL Authors: Strachan, David Peter Cooper, Philip John

PDF Published Version
Available under License Creative Commons Attribution.

Download (913kB) | Preview


The ECUAVIDA birth cohort is studying the impact of exposures to soil-transmitted helminth (STH) parasites and early-life microbial exposures on the development of atopy, allergic diseases and immune responses in childhood. A total of 2404 newborns were recruited between 2006 and 2009 in a public hospital serving the rural district of Quininde, Esmeraldas Province, in a tropical region of coastal Ecuador. Detailed measurements were done around the time of the birth, at 7 and 13 months and at 2 and 3 years, and data collection is ongoing at 5 and 8 years. Data being collected include questionnaires for: sociodemographic, lifestyle, psychosocial (at 4-6 years only) and dietary (at 6-7 years only) factors; childhood morbidity and clinical outcomes; stool samples for parasites; blood samples for DNA, measurements of vaccine responses and other measures of immune function/inflammation; and anthropometrics. Allergen skin prick test reactivity is done from 2 years and measures of airway function and inflammation at 8 years.

Item Type: Article
Additional Information: © The Author 2014. Published by Oxford University Press on behalf of the International Epidemiological Association 1517 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( 3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Epidemiology, 0104 Statistics, 1117 Public Health And Health Services
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Academic Structure > Population Health Research Institute (INPH)
Journal or Publication Title: International Journal of Epidemiology
ISSN: 1464-3685
Language: eng
2 July 2015Published
Publisher License: Creative Commons: Attribution 3.0
Project IDFunderFunder ID
088862Wellcome Trust
088862/Z/09/ZWellcome Trust
100714Wellcome Trust
AI-20565National Institute of Allergy and Infectious Diseases
R01 AI020565National Institute of Allergy and Infectious Diseases
PubMed ID: 24990475
Web of Science ID: WOS:000367178000011
Go to PubMed abstract
Publisher's version:

Actions (login required)

Edit Item Edit Item