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Improving antibiotic prescribing for children in the resource-poor setting.

Le Doare, K; Barker, CI; Irwin, A; Sharland, M (2015) Improving antibiotic prescribing for children in the resource-poor setting. British Journal of Clinical Pharmacology, 79 (3). pp. 446-455. ISSN 1365-2125 https://doi.org/10.1111/bcp.12320
SGUL Authors: Sharland, Michael Roy Barker, Charlotte Ida Sophia Le Doare, Kirsty

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Abstract

Antibiotics are a critically important part of paediatric medical care in low- and middle-income countries (LMICs), where infectious diseases are the leading cause of child mortality. The World Health Organization estimates that >50% of all medicines are prescribed, dispensed or sold inappropriately and that half of all patients do not take their medicines correctly. Given the rising prevalence of antimicrobial resistance globally, inappropriate antibiotic use is of international concern, and countries struggle to implement basic policies promoting rational antibiotic use. Many barriers to rational paediatric prescribing in LMICs persist. The World Health Organization initiatives, such as 'Make medicines child size', the Model List of Essential Medicines for Children and the Model Formulary for Children, have been significant steps forward. Continued strategies to improve access to appropriate drugs and formulations, in conjunction with improved evidence-based clinical guidelines and dosing recommendations, are essential to the success of such initiatives on both a national and an international level. This paper provides an overview of these issues and considers future developments that may improve LMIC antibiotic prescribing.

Item Type: Article
Additional Information: © 2014 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: antimicrobial pharmacotherapy, paediatrics, resistance, resource-poor setting, antimicrobial pharmacotherapy, paediatrics, resistance, resource-poor setting, Pharmacology & Pharmacy, 1115 Pharmacology And Pharmaceutical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: British Journal of Clinical Pharmacology
ISSN: 1365-2125
Language: eng
Dates:
DateEvent
March 2015Published
Projects:
Project IDFunderFunder ID
100693Wellcome TrustUNSPECIFIED
PubMed ID: 24433393
Web of Science ID: WOS:000350305800011
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/107371
Publisher's version: https://doi.org/10.1111/bcp.12320

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