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Analysis of comorbid factors that increase the COPD assessment test scores

Miyazaki, M; Nakamura, H; Chubachi, S; Sasaki, M; Haraguchi, M; Yoshida, S; Tsuduki, K; Shirahata, T; Takahashi, S; Minematsu, N; et al. Miyazaki, M; Nakamura, H; Chubachi, S; Sasaki, M; Haraguchi, M; Yoshida, S; Tsuduki, K; Shirahata, T; Takahashi, S; Minematsu, N; Koh, H; Nakamura, M; Sakamaki, F; Terashima, T; Sayama, K; Jones, PW; Asano, K; Betsuyaku, T; Keio COPD Comorbidity Research (K-CCR) Group (2014) Analysis of comorbid factors that increase the COPD assessment test scores. RESPIRATORY RESEARCH, 15 (13). ISSN 1465-993X https://doi.org/10.1186/1465-9921-15-13
SGUL Authors: Jones, Paul Wyatt

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Abstract

Background: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods: An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results: The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions: Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized

Item Type: Article
Additional Information: © 2014 Miyazaki et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Science & Technology, Life Sciences & Biomedicine, Respiratory System, RESPIRATORY SYSTEM, Chronic obstructive pulmonary disease, Health status, Depression, Gastro-esophageal reflux, Comorbidity, Osteoporosis, OBSTRUCTIVE PULMONARY-DISEASE, QUALITY-OF-LIFE, GASTROESOPHAGEAL-REFLUX DISEASE, HEALTH-STATUS, LUNG-DISEASE, OSTEOPOROSIS, EXACERBATIONS, SYMPTOMS, PREVALENCE, VALIDATION, Respiratory System, 1102 Cardiovascular Medicine And Haematology, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: RESPIRATORY RESEARCH
ISSN: 1465-993X
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Dates:
DateEvent
6 February 2014Published
Web of Science ID: WOS:000332881000001
URI: https://openaccess.sgul.ac.uk/id/eprint/107096
Publisher's version: https://doi.org/10.1186/1465-9921-15-13

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