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Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage.

Szarko, M; Xia, Y (2012) Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage. Open J Orthop, 2. pp. 1-12. ISSN 2164-3008 https://doi.org/10.4236/ojo.2012.22007
SGUL Authors: Szarko, Matthew Jordan

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Abstract

The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties. Investigations into depth-dependent mechanical properties of articular cartilage have previously required tissue modification after specimen isolation. Such modifications include histological processes, freezing, subchondral bone removal, and fluorescent staining that may alter the tissue, limiting in vivo applicability.

Item Type: Article
Additional Information: PMCID: PMC3886840
Keywords: Articular Cartilage, Cartilage Mechanics, Depth-Dependent Properties
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Biomedical Education (INMEBE)
Journal or Publication Title: Open J Orthop
ISSN: 2164-3008
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Dates:
DateEvent
1 June 2012Published
PubMed ID: 24416657
Web of Science ID: 24416657
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URI: https://openaccess.sgul.ac.uk/id/eprint/104868
Publisher's version: https://doi.org/10.4236/ojo.2012.22007

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