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Neuroablative surgical treatments for pain due to cancer.

Farrell, SM; Pereira, EAC; Brown, MRD; Green, AL; Aziz, TZ (2021) Neuroablative surgical treatments for pain due to cancer. Neurochirurgie, 67 (2). pp. 176-188. ISSN 1773-0619 https://doi.org/10.1016/j.neuchi.2020.10.003
SGUL Authors: Pereira, Erlick Abilio Coelho

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Abstract

Cancer pain is common and challenging to manage - it is estimated that approximately 30% of cancer patients have pain that is not adequately controlled by analgesia. This paper discusses safe and effective neuroablative treatment options for refractory cancer pain. Current management of cancer pain predominantly focuses on the use of medications, resulting in a relative loss of knowledge of these surgical techniques and the erosion of the skills required to perform them. Here, we review surgical methods of modulating various points of the neural axis with the aim to expand the knowledge base of those managing cancer pain. Integration of neuroablative approaches may lead to higher rates of pain relief, and the opportunity to dose reduce analgesic agents with potential deleterious side effects. With an ever-increasing population of cancer patients, it is essential that neurosurgeons maintain or train in these techniques in tandem with the oncological multi-disciplinary team.

Item Type: Article
Additional Information: © 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Cingulotomy, Cordotomy, Myelotomy, Neuroablation, Pain, Thalamotomy, Cingulotomy, Cordotomy, Myelotomy, Neuroablation, Pain, Thalamotomy, Neurology & Neurosurgery
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Neurochirurgie
ISSN: 1773-0619
Language: eng
Dates:
DateEvent
April 2021Published
29 October 2020Published Online
16 October 2020Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 33129802
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112919
Publisher's version: https://doi.org/10.1016/j.neuchi.2020.10.003

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