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Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China.

Ding, Y; Wang, Y; Hsia, Y; Russell, N; Heath, PT (2020) Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China. Emerg Infect Dis, 26 (11). pp. 2651-2659. ISSN 1080-6059 https://doi.org/10.3201/eid2611.181414
SGUL Authors: Heath, Paul Trafford

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Abstract

We performed a systematic review and meta-analysis of the incidence, case-fatality rate (CFR), isolate antimicrobial resistance patterns, and serotype and sequence type distributions for invasive group B Streptococcus (GBS) disease in infants <1-89 days of age in China. We searched the PubMed/Medline, Embase, Wanfang, and China National Knowledge Infrastructure databases for research published during January 1, 2000-March 16, 2018, and identified 64 studies. Quality of included studies was assessed by using Cochrane tools. Incidence and CFR were estimated by using random-effects meta-analyses. Overall incidence was 0.55 (95% CI 0.35-0.74) cases/1,000 live births, and the CFR was 5% (95% CI 3%-6%). Incidence of GBS in young infants in China was higher than the estimated global incidence (0.49 cases/1,000 live births) and higher than previous estimates for Asia (0.3 cases/1,000 live births). Our findings suggest that implementation of additional GBS prevention efforts in China, including maternal vaccination, could be beneficial.

Item Type: Article
Additional Information: Ding Y, Wang Y, Hsia Y, Russell N, Heath PT. Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China. Emerg Infect Dis. 2020;26(11):2651-2659. https://dx.doi.org/10.3201/eid2611.181414
Keywords: China, GBS, antimicrobial resistance, bacteria, case-fatality rate, group B Streptococcus, group B Streptococcus disease, infants, meta-analyses, newborns, respiratory infections, streptococci, systematic review, Microbiology, 1108 Medical Microbiology, 1117 Public Health and Health Services, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Emerg Infect Dis
ISSN: 1080-6059
Language: eng
Dates:
DateEvent
November 2020Published
8 October 2020Published Online
Publisher License: Publisher's own licence
Projects:
Project IDFunderFunder ID
QML 20181207Beijing Hospitals Authority Youth ProgrammeUNSPECIFIED
PubMed ID: 33079042
Web of Science ID: WOS:000596803200013
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/112752
Publisher's version: https://doi.org/10.3201/eid2611.181414

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