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Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization.

Crea, F; Bairey Merz, CN; Beltrame, JF; Berry, C; Camici, PG; Kaski, JC; Ong, P; Pepine, CJ; Sechtem, U; Shimokawa, H (2019) Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization. Eur Heart J, 40 (29). pp. 2455-2462. ISSN 1522-9645 https://doi.org/10.1093/eurheartj/ehy857
SGUL Authors: Kaski, Juan Carlos

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Abstract

Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in European Heart Journal following peer review. The version of record Filippo Crea, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Cathleen Noel Bairey Merz, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), John F Beltrame, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Colin Berry, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Paolo G Camici, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Juan Carlos Kaski, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Peter Ong, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Carl J Pepine, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Udo Sechtem, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Hiroaki Shimokawa, On behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS), Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization, European Heart Journal, Volume 40, Issue 29, 1 August 2019, Pages 2455–2462 is available online at: https://doi.org/10.1093/eurheartj/ehy857
Keywords: 1102 Cardiovascular Medicine And Haematology, Cardiovascular System & Hematology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Eur Heart J
ISSN: 1522-9645
Language: eng
Dates:
DateEvent
1 August 2019Published
4 January 2019Published Online
28 November 2018Accepted
Publisher License: Publisher's own licence
PubMed ID: 30608528
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/110640
Publisher's version: https://doi.org/10.1093/eurheartj/ehy857

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