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Vaccination in Pregnancy-Recent Developments.

Jones, CE; Calvert, A; Le Doare, K (2018) Vaccination in Pregnancy-Recent Developments. Pediatr Infect Dis J, 37 (2). pp. 191-193. ISSN 1532-0987 https://doi.org/10.1097/INF.0000000000001822
SGUL Authors: Jones, Christine Elizabeth Calvert, Anna Louise Le Doare, Kirsty

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Abstract

As early as the 19th century vaccination in pregnancy has been observed to protect both mothers and infants against smallpox, pertussis and tetanus. More recently the pace and focus of maternal vaccination has accelerated, most significantly since the influenza pandemic of 2009. Vaccination in pregnancy boosts the concentration of vaccine-specific antibody in the mother to increase antibody concentration in the infant at birth, providing protection until the period of maximum susceptibility or risk has passed or until the infant has completed the routine infant immunizations. There are now 3 vaccines, which have specific recommendations for routine use in pregnancy in an increasing number of countries, and other vaccines are progressing through clinical trials. Here we review the mechanisms of protection, the current recommendations and future prospects, and evaluation of safety of vaccines in pregnancy.

Item Type: Article
Additional Information: Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: vaccine, pregnancy, immunization, Pediatrics, 1114 Paediatrics And Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Pediatr Infect Dis J
ISSN: 1532-0987
Language: eng
Dates:
DateEvent
February 2018Published
1 November 2017Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
UNSPECIFIEDMedical Research Councilhttp://dx.doi.org/10.13039/501100000265
UNSPECIFIEDBiotechnology and Biological Sciences Research Councilhttp://dx.doi.org/10.13039/501100000268
OPP1119788Bill and Melinda Gates Foundationhttp://dx.doi.org/10.13039/100000865
12250Thrasher FoundationUNSPECIFIED
OP1153630Bill and Melinda Gates Foundationhttp://dx.doi.org/10.13039/100000865
PubMed ID: 29135826
Web of Science ID: WOS:000422929000021
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/109601
Publisher's version: https://doi.org/10.1097/INF.0000000000001822

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