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Intraspinal Pressure Monitoring in a Patient with Spinal Cord Injury Reveals Different Intradural Compartments: Injured Spinal Cord Pressure Evaluation (ISCoPE) Study.

Phang, I; Papadopoulos, MC (2015) Intraspinal Pressure Monitoring in a Patient with Spinal Cord Injury Reveals Different Intradural Compartments: Injured Spinal Cord Pressure Evaluation (ISCoPE) Study. Neurocritical Care, 23 (3). pp. 414-418. ISSN 1556-0961 https://doi.org/10.1007/s12028-015-0153-6
SGUL Authors: Papadopoulos, Marios Phang, Isaac Sng Khai

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Abstract

BACKGROUND: We recently described a technique for monitoring intraspinal pressure (ISP) after traumatic spinal cord injury (TSCI). This is analogous to intracranial pressure monitoring after brain injury. We showed that, after severe TSCI, ISP at the injury site is elevated as the swollen cord is compressed against the dura. METHODS: In a patient with complete thoracic TSCI, we sequentially monitored subdural ISP above the injury, at the injury site, and below the injury intraoperatively. Postoperatively, we simultaneously monitored subdural ISP and intraparenchymal ISP at the injury site and compared the two ISP signals as well as their Fast Fourier Transform spectra. RESULTS: Subdural ISP recorded from the injury site was higher than subdural ISP recorded from above or below the injury site by more than 10 mmHg. The subdural and intraparenchymal ISP signals recorded from the injury site had comparable amplitudes and Fast Fourier Transform spectra. Intraparenchymal pulse pressure was twofold larger than subdural pulse pressure. CONCLUSION: After severe TSCI, three intradural compartments form (space above injury, injury site, space below injury) with different ISPs. At the level of maximum spinal cord swelling (injury site), subdural ISP is comparable to intraparenchymal ISP.

Item Type: Article
Additional Information: © Springer Science+Business Media New York 2015The final publication is available at Springer via http://dx.doi.org/10.1007/s12028-015-0153-6
Keywords: Intensive care, Intraspinal pressure, Neuromonitoring, Spinal cord injury, Spinal cord perfusion pressure, Intensive care, Intraspinal pressure, Neuromonitoring, Spinal cord injury, Spinal cord perfusion pressure, Neurology & Neurosurgery, 1103 Clinical Sciences, 1109 Neurosciences
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Neuroscience (INCCNS)
Journal or Publication Title: Neurocritical Care
ISSN: 1556-0961
Language: eng
Dates:
DateEvent
1 December 2015Published
Publisher License: Publisher's own licence
PubMed ID: 26136148
Web of Science ID: WOS:000364569000017
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/108106
Publisher's version: https://doi.org/10.1007/s12028-015-0153-6

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