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Patient involvement in selection of immunosuppressive regimen following transplantation.

Popoola, J; Greene, H; Kyegombe, M; MacPhee, IA (2014) Patient involvement in selection of immunosuppressive regimen following transplantation. Patient Preference and Adherence, 8. pp. 1705-1712. ISSN 1177-889X https://doi.org/10.2147/PPA.S38987
SGUL Authors: MacPhee, Iain Angus MacGregor Popoola, Joyce

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Abstract

Transplantation has made a considerable difference to the lives of many patients. However, feedback from patients indicates that although having a transplant is a hugely positive experience, having to take medications indefinitely is one of the biggest challenges. An ideal scenario would be no medications following a transplant. A compromise would be a minimal number of medications, with minimal restrictions and as simple a regimen as possible. Although there is considerable research going into fine-tuning the management of the immune response to a transplant, to date there is no universal regimen that enables patients to remain free of immunosuppressant medications, making adherence paramount to maintain long-term allograft survival. This paper reviews the available immunosuppressant regimens and factors influencing choice from both the clinician's and the patient's perspective. Factors influencing the decision-making process, such as quality of life for patients, their satisfaction, acceptability, and adherence uptake are reviewed. We conclude with a further assessment of patient choice as a factor in regimen selection, its impact on adherence, and its implications.

Item Type: Article
Additional Information: © 2014 Popoola et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
Keywords: adherence, allograft, decision-making, immunosuppressants, patient involvement, satisfaction, transplant, adherence, transplant, allograft, immunosuppressants, patient involvement, satisfaction, decision-making, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Patient Preference and Adherence
ISSN: 1177-889X
Language: eng
Dates:
DateEvent
12 December 2014Published
PubMed ID: 25525347
Web of Science ID: WOS:000346246000001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/107347
Publisher's version: https://doi.org/10.2147/PPA.S38987

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