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Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome.

Walsh, DJ; Sills, ES; Shkrobot, LV; Gleeson, NC; Sheppard, MN; Walsh, AP (2009) Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome. World Journal of Surgical Oncology, 7 (46). ISSN 1477-7819 https://doi.org/10.1186/1477-7819-7-46
SGUL Authors: Sheppard, Mary Noelle

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Abstract

BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer. CASE PRESENTATION: Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well. CONCLUSION: Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here.

Item Type: Article
Additional Information: © 2009 Walsh et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Adult, Cystadenocarcinoma, Serous, Female, Fertilization in Vitro, Humans, Ovarian Neoplasms, Pregnancy, Pregnancy Complications, Neoplastic, Science & Technology, Life Sciences & Biomedicine, Oncology, Surgery, NEEDLE-ASPIRATION-CYTOLOGY, CYSTS, FERTILIZATION PATIENTS, Oncology & Carcinogenesis, 1103 Clinical Sciences, 1112 Oncology And Carcinogenesis
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Cardiac (INCCCA)
Journal or Publication Title: World Journal of Surgical Oncology
ISSN: 1477-7819
Language: eng
Dates:
DateEvent
14 May 2009Published
PubMed ID: 19442277
Web of Science ID: WOS:000266536600001
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/107218
Publisher's version: https://doi.org/10.1186/1477-7819-7-46

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