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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

O'Keefe, BR; Vojdani, F; Buffa, V; Shattock, RJ; Montefiori, DC; Bakke, J; Mirsalis, J; d'Andrea, AL; Hume, SD; Bratcher, B; et al. O'Keefe, BR; Vojdani, F; Buffa, V; Shattock, RJ; Montefiori, DC; Bakke, J; Mirsalis, J; d'Andrea, AL; Hume, SD; Bratcher, B; Saucedo, CJ; McMahon, JB; Pogue, GP; Palmer, KE (2009) Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106 (15). 6099 - 6104 (6). ISSN 0027-8424 https://doi.org/10.1073/pnas.0901506106
SGUL Authors: Shattock, Robin John

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Item Type: Article
Additional Information: PubMed ID: 19332801
Keywords: Algal Proteins, Animals, Cell Proliferation, Cells, Cultured, Cervix Uteri, Cytokines, Drug Evaluation, Preclinical, Female, HIV Envelope Protein gp120, HIV Fusion Inhibitors, HIV Infections, HIV-1, Humans, Lectins, Plant Lectins, Protein Binding, Rabbits, Tissue Culture Techniques, Tissue Transplantation, Tobacco, Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, AIDS, lectin, plant, sexually transmitted, tobacco mosaic virus, IMMUNODEFICIENCY-VIRUS TYPE-1, HUMAN CERVICAL TISSUE, ANTIVIRAL PROTEIN GRIFFITHSIN, CYANOVIRIN-N, VAGINAL TRANSMISSION, ENV CLONES, INFECTION, MACAQUES, PREVENTION, FUSION, AIDS, lectin, plant, sexually transmitted, tobacco mosaic virus
Journal or Publication Title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN: 0027-8424
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Dates:
DateEvent
14 April 2009Published
Web of Science ID: WOS:000265174600015
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URI: http://openaccess.sgul.ac.uk/id/eprint/397
Publisher's version: https://doi.org/10.1073/pnas.0901506106

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