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Delivering multi-disease screening to migrants for latent TB and blood-borne viruses in an emergency department setting: A feasibility study.

Hargreaves, S; Nellums, LB; Johnson, C; Goldberg, J; Pantelidis, P; Rahman, A; Friedland FMedSci, JS (2020) Delivering multi-disease screening to migrants for latent TB and blood-borne viruses in an emergency department setting: A feasibility study. Travel Med Infect Dis. p. 101611. ISSN 1873-0442
SGUL Authors: Hargreaves, Sally

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BACKGROUND: Screening for latent tuberculosis infection (LTBI) in migrants is important for elimination of tuberculosis in low-incidence countries, alongside the need to detect blood-borne infections to align with new guidelines on migrant screening for multiple infections in European countries. However, feasibility needs to be better understood. METHODS: We did a feasibility study to test an innovative screening model offering combined testing for LTBI (QuantiFERON), HIV, hepatitis B/C in a UK emergency department, with two year follow-up. RESULTS: 96 economic migrants, asylum seekers and refugees from 43 countries were screened (46 [47.9%] women; mean age 35.2 years [SD 11.7; range 18-73]; mean time in the UK 4.8 years [SD 3.2; range 0-10]). 14 migrants (14.6%) tested positive for LTBI alongside HIV [1], hepatitis B [2], and hepatitis C [1] Of migrants with LTBI, 5 (35.7%) were successfully engaged in treatment. 74 (77.1%) migrants reported no previous screening since migrating to the UK. CONCLUSION: Multi-disease screening in this setting is feasible and merits being further tested in larger-scale studies. However, greater emphasis must be placed on ensuring successful treatment outcomes. We identified major gaps in current screening provision; most had no prior screening despite several years since migration, which holds major relevance to other European countries.

Item Type: Article
Additional Information: © 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
Keywords: Europe, HIV, Health-service delivery, Hepatitis, LTBI, Latent TB, Migrant, Multi-disease screening, 1103 Clinical Sciences, 1117 Public Health and Health Services, Tropical Medicine
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Travel Med Infect Dis
ISSN: 1873-0442
Language: eng
29 February 2020Published Online
26 February 2020Accepted
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Project IDFunderFunder ID
209993/Z/17/ZWellcome Trust
UNSPECIFIEDNational Institute for Health Research
UNSPECIFIEDEuropean Society for Clinical Microbiology and Infectious DiseasesUNSPECIFIED
PubMed ID: 32126293
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