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Trying to keep calm in troubled times: The role of K channels in uterine physiology

Greenwood, IA (2020) Trying to keep calm in troubled times: The role of K channels in uterine physiology. CURRENT OPINION IN PHYSIOLOGY, 13. pp. 1-5. ISSN 2468-8673 https://doi.org/10.1016/j.cophys.2019.07.005
SGUL Authors: Greenwood, Iain Andrew

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Abstract

Much research has been undertaken to define what determines the inherent contractility of the myometrial smooth muscle and what dictates the switch from relaxed to contractile phenotype. While a lot has been deciphered the fundamental mechanisms that initiate and maintain the switch in uterine physiology are ill defined. Uterine physiology is indubitably complex so this article focuses on one piece of the puzzle: the role of certain potassium channels in determining myometrial contractility and how altered activity may contribute to the hyper-contractile uterus at term.

Item Type: Article
Additional Information: © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ Correction available at https://doi.org/10.1016/j.cophys.2020.03.002
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: CURRENT OPINION IN PHYSIOLOGY
ISSN: 2468-8673
Dates:
DateEvent
February 2020Published
25 July 2019Published Online
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Projects:
Project IDFunderFunder ID
MR/K019074/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
PG/12/63/29824British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
PG/14/57/30992British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
PG/15/97/31862British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
6553Novo Nordiskhttp://dx.doi.org/10.13039/501100004191
Web of Science ID: WOS:000508006800002
URI: http://openaccess.sgul.ac.uk/id/eprint/111639
Publisher's version: https://doi.org/10.1016/j.cophys.2019.07.005

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