Sathe, A;
Tillman, H;
Coles, LD;
Elm, JJ;
Silbergleit, R;
Chamberlain, J;
Kapur, J;
Cock, HR;
Fountain, NB;
Shinnar, S;
et al.
Sathe, A; Tillman, H; Coles, LD; Elm, JJ; Silbergleit, R; Chamberlain, J; Kapur, J; Cock, HR; Fountain, NB; Shinnar, S; Lowenstein, DH; Conwit, RA; Bleck, TP; Cloyd, JC
(2019)
Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial.
ACADEMIC EMERGENCY MEDICINE, 26 (8).
pp. 940-943.
ISSN 1069-6563
https://doi.org/10.1111/acem.13811
SGUL Authors: Cock, Hannah Rutherford
![[img]](https://openaccess.sgul.ac.uk/110886/1.hassmallThumbnailVersion/BZD%20manuscript-%20AEM%20Research%20letter-submission%20proof.pdf)  Preview |
|
PDF
Accepted Version
Available under License ["licenses_description_publisher" not defined].
Download (950kB)
| Preview
|
Abstract
Benzodiazepines, including diazepam (DZP), lorazepam (LZP), and midazolam (MDZ), are considered the initial drugs of choice for status epilepticus (SE) treatment. A number of trials have demonstrated their safety and efficacy; however, the failure rate ranges from 10‐55%.1,2 This may be attributable, in part, to sub‐optimal benzodiazepine dosing and timing of administration.
The Neurocritical Care Society (NCS) and American Epilepsy Society (AES) have published evidence‐based guidelines for benzodiazepine use in SE that specify drugs, doses, and routes of administration.
| Item Type: |
Article
|
| Additional Information: |
This is the peer reviewed version of the following article: Sathe, A. G., Tillman, H. , Coles, L. D., Elm, J. J., Silbergleit, R. , Chamberlain, J. , Kapur, J. , Cock, H. R., Fountain, N. B., Shinnar, S. , Lowenstein, D. H., Conwit, R. A., Bleck, T. P. and Cloyd, J. C. (2019), Underdosing of Benzodiazepines in Patients with Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial. Academic Emergency Medicine 2019; 26: 940– 943, which has been published in final form at [https://doi.org/10.1111/acem.13811. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Keywords: |
1103 Clinical Sciences, 1117 Public Health And Health Services, Emergency & Critical Care Medicine |
| SGUL Research Institute / Research Centre: |
Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE ) |
| Journal or Publication Title: |
ACADEMIC EMERGENCY MEDICINE |
| ISSN: |
1069-6563 |
| Dates: |
| Date | Event |
|---|
| 12 August 2019 | Published | | 18 July 2019 | Published Online | | 26 May 2019 | Accepted |
|
| Publisher License: |
Publisher's own licence |
| Projects: |
|
| URI: |
https://openaccess.sgul.ac.uk/id/eprint/110886 |
| Publisher's version: |
https://doi.org/10.1111/acem.13811 |
Statistics
Item downloaded times since 28 May 2019.
Actions (login required)
 |
Edit Item |
