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Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization.

Crea, F; Bairey Merz, CN; Beltrame, JF; Berry, C; Camici, PG; Kaski, JC; Ong, P; Pepine, CJ; Sechtem, U; Shimokawa, H (2019) Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization. Eur Heart J. ISSN 1522-9645 https://doi.org/10.1093/eurheartj/ehy857
SGUL Authors: Kaski, Juan Carlos

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Abstract

Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in European Heart Journal following peer review. The version of record Filippo Crea, Cathleen Noel Bairey Merz, John F Beltrame, Colin Berry, Paolo G Camici, Juan Carlos Kaski, Peter Ong, Carl J Pepine, Udo Sechtem, Hiroaki Shimokawa; Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization, European Heart Journal, , ehy857 is available online at: https://doi.org/10.1093/eurheartj/ehy857
Keywords: 1102 Cardiovascular Medicine And Haematology, Cardiovascular System & Hematology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Eur Heart J
ISSN: 1522-9645
Language: eng
Dates:
DateEvent
4 January 2019Published Online
28 November 2018Accepted
Publisher License: Publisher's own licence
PubMed ID: 30608528
Go to PubMed abstract
URI: http://openaccess.sgul.ac.uk/id/eprint/110640
Publisher's version: https://doi.org/10.1093/eurheartj/ehy857

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