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Interventions to Improve Vaccination Uptake and Cost Effectiveness of Vaccination Strategies in Newly Arrived Migrants in the EU/EEA: A Systematic Review.

Hui, C; Dunn, J; Morton, R; Staub, LP; Tran, A; Hargreaves, S; Greenaway, C; Biggs, BA; Christensen, R; Pottie, K (2018) Interventions to Improve Vaccination Uptake and Cost Effectiveness of Vaccination Strategies in Newly Arrived Migrants in the EU/EEA: A Systematic Review. Int J Environ Res Public Health, 15 (10). p. 2065. ISSN 1660-4601 https://doi.org/10.3390/ijerph15102065
SGUL Authors: Hargreaves, Sally

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Abstract

Newly arrived migrants to the EU/EEA (arrival within the past five years), as well as other migrant groups in the region, might be under-immunised and lack documentation of previous vaccinations, putting them at increased risk of vaccine-preventable diseases circulating in Europe. We therefore performed a systematic review conforming to PRISMA guidelines (PROSPERO CRD42016045798) to explore: (i) interventions that improve vaccine uptake among migrants; and (ii) cost-effectiveness of vaccination strategies among this population. We searched MEDLINE, Embase, CINAHL, and Cochrane Database of Systematic Reviews (CDSR) between 1 January 2006 to 18 June 2018. We included three primary intervention studies performed in the EU/EEA or high-income countries and one cost effectiveness study relevant to vaccinations in migrants. Intervention studies showed small but promising impact only on vaccine uptake with social mobilization/community outreach, planned vaccination programs and education campaigns. Targeting migrants for catch-up vaccination is cost effective for presumptive vaccination for diphtheria, tetanus, and polio, and there was no evidence of benefit of carrying out pre-vaccination serological testing. The cost-effectiveness is sensitive to the seroprevalence and adherence to vaccinations of the migrant. We conclude that scarce but direct EU/EEA data suggest social mobilization, vaccine programs, and education campaigns are promising strategies for migrants, but more research is needed. Research should also study cost effectiveness of strategies. Vaccination of migrants should continue to be a public heath priority in EU/EEA.

Item Type: Article
Additional Information: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: VPD, cost effectiveness, health systems, immunisation strategies, migrants, refugees, MD Multidisciplinary, Toxicology
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Int J Environ Res Public Health
ISSN: 1660-4601
Language: eng
Dates:
DateEvent
20 September 2018Published
7 September 2018Accepted
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
1054216National Health and Medical Research Councilhttp://dx.doi.org/10.13039/501100000925
209993/Z/17/ZWellcome Trusthttp://dx.doi.org/10.13039/100004440
PubMed ID: 30241320
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/110203
Publisher's version: https://doi.org/10.3390/ijerph15102065

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