Tuberculous arthritis: negative Xpert MTB/RIF assay does not rule out infection!

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Davis, R; Higgens, C; Cosgrove, C; Shur, J; Arkell, P (2018) Tuberculous arthritis: negative Xpert MTB/RIF assay does not rule out infection! BMJ Case Rep, 2018. ISSN 1757-790X https://doi.org/10.1136/bcr-2018-224288
SGUL Authors: Cosgrove, Catherine

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Abstract

We present a case of a 31-year-old man of Indian origin with no previous medical history who presented with an inflamed knee. Treatment for bacterial infection was unsuccessful, and needle aspiration of the left knee effusion/collection was smear and culture positive for tuberculosis (TB), despite Xpert MTB/RIF being falsely negative. The patient was commenced on quadruple therapy for TB and within 2 months had improved significantly with no clinical evidence of ongoing inflammation.

Item Type:

Article

Additional Information:

This article has been accepted for publication in BMJ Case Reports following peer review. The definitive copyedited, typeset version is available online at http://casereports.bmj.com/content/2018/bcr-2018-224288

Keywords:

bone and joint infections, infections, infectious diseases, musculoskeletal and joint disorders, tb and other respiratory infections, bone and joint infections, infections, infectious diseases, musculoskeletal and joint disorders, tb and other respiratory infections

SGUL Research Institute / Research Centre:

Academic Structure > Infection and Immunity Research Institute (INII)

Journal or Publication Title:

BMJ Case Rep

ISSN:

1757-790X

Language:

eng

Dates: