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Dynamic Tissue Rearrangements during Vertebrate Eye Morphogenesis: Insights from Fish Models.

Cavodeassi, F (2018) Dynamic Tissue Rearrangements during Vertebrate Eye Morphogenesis: Insights from Fish Models. J Dev Biol, 6 (1). p. 4. ISSN 2221-3759 https://doi.org/10.3390/jdb6010004
SGUL Authors: Cavodeassi, Florencia

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Abstract

Over the last thirty years, fish models, such as the zebrafish and medaka, have become essential to pursue developmental studies and model human disease. Community efforts have led to the generation of wide collections of mutants, a complete sequence of their genomes, and the development of sophisticated genetic tools, enabling the manipulation of gene activity and labelling and tracking of specific groups of cells during embryonic development. When combined with the accessibility and optical clarity of fish embryos, these approaches have made of them an unbeatable model to monitor developmental processes in vivo and in real time. Over the last few years, live-imaging studies in fish have provided fascinating insights into tissue morphogenesis and organogenesis. This review will illustrate the advantages of fish models to pursue morphogenetic studies by highlighting the findings that, in the last decade, have transformed our understanding of eye morphogenesis.

Item Type: Article
Additional Information: © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: eye, live-imaging, morphogenesis
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Biomedical Education (INMEBE)
Journal or Publication Title: J Dev Biol
ISSN: 2221-3759
Language: eng
Dates:
DateEvent
28 February 2018Published
27 February 2018Accepted
Publisher License: Creative Commons: Attribution 4.0
PubMed ID: 29615553
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/109731
Publisher's version: https://doi.org/10.3390/jdb6010004

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