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Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force.

Fischer, P; Pogosyan, A; Cheeran, B; Green, AL; Aziz, TZ; Hyam, J; Little, S; Foltynie, T; Limousin, P; Zrinzo, L; et al. Fischer, P; Pogosyan, A; Cheeran, B; Green, AL; Aziz, TZ; Hyam, J; Little, S; Foltynie, T; Limousin, P; Zrinzo, L; Hariz, M; Samuel, M; Ashkan, K; Brown, P; Tan, H (2017) Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force. Exp Neurol, 293. pp. 53-61. ISSN 1090-2430 https://doi.org/10.1016/j.expneurol.2017.03.015
SGUL Authors: Cheeran, Binith

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Abstract

Motor imagery involves cortical networks similar to those activated by real movements, but the extent to which the basal ganglia are recruited is not yet clear. Gamma and beta oscillations in the subthalamic nucleus (STN) vary with the effort of sustained muscle activity. We recorded local field potentials in Parkinson's disease patients and investigated if similar changes can be observed during imagined gripping at three different 'forces'. We found that beta activity decreased significantly only for imagined grips at the two stronger force levels. Additionally, gamma power significantly scaled with increasing imagined force. Thus, in combination, these two spectral features can provide information about the intended force of an imaginary grip even in the absence of sensory feedback. Modulations in the two frequency bands during imaginary movement may explain the rehabilitating benefit of motor imagery to improve motor performance. The results also suggest that STN LFPs may provide useful information for brain-machine interfaces.

Item Type: Article
Additional Information: © 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Basal ganglia, Beta suppression, Brain computer interface, Brain machine interface, Force decoding, Gamma oscillations, Imagined force, Motor imagery, Neuro-feedback, STN, Neurology & Neurosurgery, 1109 Neurosciences, 1103 Clinical Sciences, 1701 Psychology
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Journal or Publication Title: Exp Neurol
ISSN: 1090-2430
Language: eng
Dates:
DateEvent
22 March 2017Accepted
22 March 2017Published Online
July 2017Published
Publisher License: Creative Commons: Attribution 4.0
Projects:
Project IDFunderFunder ID
MC_UU_12024/1Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
PubMed ID: 28342747
Go to PubMed abstract
URI: http://openaccess.sgul.ac.uk/id/eprint/108797
Publisher's version: https://doi.org/10.1016/j.expneurol.2017.03.015

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