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Intensive Care Admissions for Children With Enterovirus and Human Parechovirus Infections in the United Kingdom and The Republic of Ireland, 2010-2014.

Braccio, S; Kapetanstrataki, M; Sharland, M; Ladhani, SN (2017) Intensive Care Admissions for Children With Enterovirus and Human Parechovirus Infections in the United Kingdom and The Republic of Ireland, 2010-2014. Pediatr Infect Dis J, 36 (3). pp. 339-342. ISSN 1532-0987 https://doi.org/10.1097/INF.0000000000001430
SGUL Authors: Sharland, Michael Roy Ladhani, Shamez Nizarali

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Abstract

Enteroviruses and human parechoviruses usually cause mild, self-limiting illnesses in children but can occasionally cause severe disease. During 2010-2014, 104 children in the United Kingdom and the Republic of Ireland were admitted to a pediatric intensive care unit with severe enterovirus and human parechovirus infection; 40% had neurologic symptoms, 20% respiratory failure, 16% cardiac complications and 11% septic shock. Annual number of cases and incidence increased in the 5-year period, from 0.6/1000 pediatric intensive care unit admissions (12 cases) in 2010 to 1.8/1000 (36 cases) in 2014. Most cases (n = 86, 83%) were younger than 1 year; 77% (n = 80) required invasive ventilation, 40% (n = 42) inotropic support, 4% (n = 4) renal dialysis and 3% (n = 3) extracorporeal membrane oxygenation. Eight children (8%) died, including 4 with cardiac complications.

Item Type: Article
Additional Information: This is a non-final version of an article published in final form in Braccio, Serena MRCPCH; Kapetanstrataki, Melpo MSc; Sharland, Mike FRCPCH; Ladhani, Shamez N. MRCPCH, PhD, Intensive Care Admissions for Children With Enterovirus and Human Parechovirus Infections in the United Kingdom and The Republic of Ireland, 2010-2014.[Report], Pediatric Infectious Disease Journal. 36(3):339-342, March 2017.
Keywords: Pediatrics, 1114 Paediatrics And Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Infection and Immunity Research Institute (INII)
Journal or Publication Title: Pediatr Infect Dis J
ISSN: 1532-0987
Language: eng
Dates:
DateEvent
March 2017Published
13 December 2016Published Online
16 August 2016Accepted
Publisher License: Publisher's own licence
PubMed ID: 27977558
Go to PubMed abstract
URI: http://openaccess.sgul.ac.uk/id/eprint/108477
Publisher's version: https://doi.org/10.1097/INF.0000000000001430

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