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Multilevel regression modelling to investigate variation in disease prevalence across locations

Weinmayr, G; Dreyhaupt, J; Jaensch, A; Forastiere, F; Strachan, DP (2017) Multilevel regression modelling to investigate variation in disease prevalence across locations. International Journal of Epidemiology, 46 (1). pp. 338-347. ISSN 1464-3685 https://doi.org/10.1093/ije/dyw274
SGUL Authors: Strachan, David Peter

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Abstract

In this article, we show how to investigate the role of individual (personal) risk factors in outcome prevalence in multicentre studies with multilevel modelling. The variation in outcome prevalence is modelled by introducing a random intercept. In the next step, the empty model is compared with the model containing the risk factor(s). Because the outcome is dichotomous, this comparison can only be carried out after having rescaled the models’ parameter values to the variance of an underlying continuous variable. We illustrate this approach with data from Phase Two of the International Study of Asthma and Allergies in Childhood (ISAAC) and provide a corresponding Stata do-file.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in International Journal of Epidemiology following peer review. The version of record Weinmayr, G; Dreyhaupt, J; Jaensch, A; Forastiere, F; Strachan, DP (2017) Multilevel regression modelling to investigate variation in disease prevalence across locations. International Journal of Epidemiology, 46 (1). pp. 338-347 is available online at: http://dx.doi.org/10.1093/ije/dyw274.
Keywords: Epidemiology, 0104 Statistics, 1117 Public Health And Health Services
SGUL Research Institute / Research Centre: Academic Structure > Population Health Research Institute (INPH)
Journal or Publication Title: International Journal of Epidemiology
ISSN: 1464-3685
Dates:
DateEvent
February 2017Published
17 November 2016Published Online
2 September 2016Accepted
Publisher License: Publisher's own licence
Projects:
Project IDFunderFunder ID
WE 4306/3-1Deutsche Forschungsgemeinschafthttp://dx.doi.org/10.13039/501100001659
URI: https://openaccess.sgul.ac.uk/id/eprint/108401
Publisher's version: https://doi.org/10.1093/ije/dyw274

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