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Relationship between outdoor temperature and cardiovascular disease risk factors in older people.

Sartini, C; Barry, SJ; Whincup, PH; Wannamethee, SG; Lowe, GDO; Jefferis, BJ; Lennon, L; Welsh, P; Ford, I; Sattar, N; et al. Sartini, C; Barry, SJ; Whincup, PH; Wannamethee, SG; Lowe, GDO; Jefferis, BJ; Lennon, L; Welsh, P; Ford, I; Sattar, N; Morris, RW (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. Eur J Prev Cardiol, 24 (4). pp. 349-356. ISSN 2047-4881 https://doi.org/10.1177/2047487316682119
SGUL Authors: Whincup, Peter Hynes

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Abstract

Background Previous studies demonstrated that lower outdoor temperatures increase the levels of established cardiovascular disease risk factors, such as blood pressure and lipids. Whether or not low temperatures increase novel cardiovascular disease risk factors levels is not well studied. The aim was to investigate associations of outdoor temperature with a comprehensive range of established and novel cardiovascular disease risk factors in two large Northern European studies of older adults, in whom cardiovascular disease risk is increased. Design and methods Data came from the British Regional Heart Study (4252 men aged 60-79 years) and the Prospective Study of Pravastatin in the Elderly at Risk (5804 men and women aged 70-82 years). Associations between outdoor temperature and cardiovascular disease risk factors were quantified in each study and then pooled using a random effects model. Results With a 5℃ lower mean temperature, total cholesterol was 0.04 mmol/l (95% confidence interval (CI) 0.02-0.07) higher, low density lipoprotein cholesterol was 0.02 mmol/l (95% CI 0.01-0.05) higher and SBP was 1.12 mm Hg (95% CI 0.60-1.64) higher. Among novel cardiovascular disease risk factors, C-reactive protein was 3.3% (95% CI 1.0-5.6%) higher, interleukin-6 was 2.7% (95% CI 1.1-4.3%) higher, and vitamin D was 11.2% (95% CI 1.0-20.4%) lower. Conclusions Lower outdoor temperature was associated with adverse effects on cholesterol, blood pressure, circulating inflammatory markers, and vitamin D in two older populations. Public health approaches to protect the elderly against low temperatures could help in reducing the levels of several cardiovascular disease risk factors.

Item Type: Article
Additional Information: This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Keywords: Biomarkers, cardiovascular disease risk factors, older adults, outdoor temperature
SGUL Research Institute / Research Centre: Academic Structure > Population Health Research Institute (INPH)
Journal or Publication Title: Eur J Prev Cardiol
ISSN: 2047-4881
Language: eng
Dates:
DateEvent
1 March 2017Published
10 November 2016Accepted
5 December 2016Published Online
Publisher License: Creative Commons: Attribution 3.0
Projects:
Project IDFunderFunder ID
PG/13/41/30304British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
RG/13/16/30528British Heart Foundationhttp://dx.doi.org/10.13039/501100000274
PubMed ID: 27899528
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/108388
Publisher's version: https://doi.org/10.1177/2047487316682119

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