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Role of uteroplacental and fetal Doppler in identifying fetal growth restriction at term.

Khalil, A; Thilaganathan, B (2017) Role of uteroplacental and fetal Doppler in identifying fetal growth restriction at term. Best Practice & Research: Clinical Obstetrics & Gynaecology, 38. pp. 38-47. ISSN 1532-1932 https://doi.org/10.1016/j.bpobgyn.2016.09.003
SGUL Authors: Thilaganathan, Baskaran Khalil, Asma

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Abstract

Identification of the fetus at risk of adverse outcome at term is a challenge to both clinicians and researchers alike. Despite the fact that fetal growth restriction (FGR) is a known risk factor for stillbirth, at least two thirds of the stillbirth cases at term are not small for gestational age (SGA) - a commonly used proxy for FGR. However, the majority of SGA fetuses are constitutionally small babies and do not suffer from adverse perinatal outcome. The cerebroplacental ratio (CPR) is emerging as a marker of failure to reach growth potential at term. CPR is an independent predictor of intrapartum fetal distress, admission to the neonatal unit at term, stillbirth, perinatal death and neonatal morbidity. Raised uterine artery Doppler resistance in the third trimester is independently associated with significantly lower birthweight and CPR. The combination of the estimated fetal weight, CPR and uterine Doppler in the third trimester can identify the majority of fetuses at risk of stillbirth.

Item Type: Article
Additional Information: © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: cerberoplacental, failure to reach growth potential, fetal growth restriction, middle cerebral artery Doppler, ratio, umbilical artery Doppler, uteroplacental Doppler, 1114 Paediatrics And Reproductive Medicine
SGUL Research Institute / Research Centre: Academic Structure > Molecular and Clinical Sciences Research Institute (MCS)
Academic Structure > Molecular and Clinical Sciences Research Institute (MCS) > Vascular (INCCVA)
Journal or Publication Title: Best Practice & Research: Clinical Obstetrics & Gynaecology
ISSN: 1532-1932
Language: ENG
Dates:
DateEvent
23 September 2016Published Online
16 September 2016Accepted
1 January 2017Published
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 27720309
Go to PubMed abstract
URI: http://openaccess.sgul.ac.uk/id/eprint/108301
Publisher's version: https://doi.org/10.1016/j.bpobgyn.2016.09.003

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