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The pharmacological management of psychiatric comorbidities in patients with epilepsy.

Mula, M (2016) The pharmacological management of psychiatric comorbidities in patients with epilepsy. Pharmacological Research, 107. pp. 147-153. ISSN 1096-1186 https://doi.org/10.1016/j.phrs.2016.03.022
SGUL Authors: Mula, Marco

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Abstract

Psychiatric disorders represent a frequent comorbidity in patients with epilepsy affecting quality of life, morbidity and mortality. Evidence-based data on the management of these conditions are limited but a number of recommendations are now available to guide clinical practice. The present paper reviews the pharmacological treatment of psychiatric problems in epilepsy with special attention to data coming from randomised controlled trials (RCTs), pharmacological interactions with AEDs and the issue of seizure worsening during treatment with psychotropic drugs. Epidemiologically or clinically relevant psychiatric conditions are discussed namely mood and anxiety disorders, psychoses and attention deficit hyperactivity disorder.

Item Type: Article
Additional Information: © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Antidepressant drugs, Antiepileptic drugs, Antipsychotic drugs, Anxiety, Attention deficit hyperactivity disorder, Depression, Epilepsy, Interactions, Methylphenidate, Psychosis, Antidepressant drugs, Antiepileptic drugs, Antipsychotic drugs, Anxiety, Attention deficit hyperactivity disorder, Depression, Epilepsy, Interactions, Methylphenidate, Psychosis, Pharmacology & Pharmacy, 1115 Pharmacology And Pharmaceutical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Pharmacological Research
ISSN: 1096-1186
Language: eng
Dates:
DateEvent
1 May 2016Published
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 27001226
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/107954
Publisher's version: https://doi.org/10.1016/j.phrs.2016.03.022

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