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Anxiety disorders in people with epilepsy.

Brandt, C; Mula, M (2016) Anxiety disorders in people with epilepsy. Epilepsy Behavior, 59. pp. 87-91. ISSN 1525-5069 https://doi.org/10.1016/j.yebeh.2016.03.020
SGUL Authors: Mula, Marco

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Abstract

Anxiety disorders are frequent, though probably underdiagnosed, comorbidities in epilepsy. Epilepsy and anxiety may share common neurobiological correlates as shown in animal models and suggested by studies demonstrating anxiety disorders before the manifestation of epilepsy. Comorbid anxiety disorders have a major impact on the affected patients' quality of life and may increase the risk for suicidality. Successful treatment of the epilepsy may alleviate anxiety symptoms. Treatment of anxiety is based on selective serotonin reuptake inhibitors, benzodiazepines (although only as second-line choices), and psychotherapy. Specific AEDs (especially pregabalin) have been shown to have anxiolytic properties. This paper is aimed at reviewing anxiety disorders in patients with epilepsy discussing current scientific evidence about pathophysiology, clinical aspects, and treatment strategies.

Item Type: Article
Additional Information: © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Comorbidity, Diagnosis, Prevalence, Quality of life, Treatment, Neurology & Neurosurgery, 1103 Clinical Sciences
SGUL Research Institute / Research Centre: Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Clinical Education (INMECE )
Journal or Publication Title: Epilepsy Behavior
ISSN: 1525-5069
Language: eng
Dates:
DateEvent
1 June 2016Published
Publisher License: Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
PubMed ID: 27116536
Go to PubMed abstract
URI: https://openaccess.sgul.ac.uk/id/eprint/107953
Publisher's version: https://doi.org/10.1016/j.yebeh.2016.03.020

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